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  <titleInfo>
    <title>Revisão das Propriedades Medicinais de Cajanus cajan na Doença Falciforme</title>
  </titleInfo>
  <name type="personal">
    <namePart>Cordovil, K.</namePart>
    <role>
      <roleTerm authority="marcrelator" type="text">creator</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Cople-Rodrigues, C.S.</namePart>
    <role>
      <roleTerm authority="marcrelator" type="text">creator</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Santos, I.N.</namePart>
    <role>
      <roleTerm authority="marcrelator" type="text">creator</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Franco, E.D.</namePart>
    <role>
      <roleTerm authority="marcrelator" type="text">creator</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Bertolucci, S.K.V.</namePart>
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  <genre authority="marc">abstract or summary</genre>
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  <abstract>

RESUMO: 

Este artigo descreve a ocorrência, características botânicas, fitoquímicas e a
composição nutricional do feijão guandu [Cajanus cajan (L.) Millsp], e sua relação no processo
de inibição da falcização na doença falciforme, um distúrbio genético que acomete as hemácias,
gerando hemólise e anemia crônica. Dois constituintes químicos estariam mais relacionados aos
efeitos inibitórios na falcização de células falciformes: L-fenilalanina e o ácido p-hidroxibenzóico.
Estudos químico-biológicos detalhados com o feijão guandu no Brasil poderão esclarecer melhor
os mecanismos pelos quais ocorre a inibição da falcização das hemácias e a diminuição do
estresse oxidativo, ajudando no tratamento de pessoas com DF.

Palavras-chave: propriedades medicinais, cajanus cajan, anemia falciforme.</abstract>
  <abstract>

ABSTRACT: 

Review of Medicinal Cajanus cajan of properties in Sickle Cell Disease.
This article describes the occurrence, botanical characteristics, phytochemical and nutritional
composition of pigeonpea [Cajanus cajan (L.) Millsp], and their relationship in the process
inhibition of sickling in sickle cell disease (SCD), a genetic disorder that affects red blood cells,
causing hemolysis and chronic anemia. Two chemical components would be related to the
inhibitory effect on sickling of sickle cells: the L-phenylalanine and the p- hydroxybenzoic acid.
In Brazil, detailed studies with pigeonpea chemical-biological may clarify the mechanisms by
which the inhibition of sickling of red blood cells occurs, reducing oxidative stress and thus
helping treating people affected by this disease.

Keywords: medicinal properties, cajanus cajan, sickle cell anemia.</abstract>
  <note>Publicação on-line; Bibliography p. 1205-1207 (65 ref.); 3 tables; Summaries (En, Pt)</note>
  <subject>
    <topic>COMPOSIÇÃO BOTÂNICA</topic>
  </subject>
  <subject>
    <topic>PLANTA MEDICINAL</topic>
  </subject>
  <subject>
    <topic>CAJANUS CAJAN</topic>
  </subject>
  <subject>
    <topic>ANEMIA</topic>
  </subject>
  <relatedItem type="host">
    <titleInfo>
      <title>Revista Brasileira de Plantas Medicinais (Brazil)</title>
    </titleInfo>
    <originInfo>
      <publisher>Botucatu-SP Instituto de Biociências - Departamento de Química e Bioquímica 1998</publisher>
    </originInfo>
    <identifier>2024-2525</identifier>
    <identifier type="issn">1516-0572</identifier>
    <identifier type="local">BR2024001458</identifier>
    <part>
      <text>v. 17(4 suppl. 3) p. 1199-1207; (2015)</text>
    </part>
  </relatedItem>
  <identifier type="uri">https://www.scielo.br/j/rbpm/a/hyBMLMXfCknGbPQjpkmxZrg/?format=pdf&amp;lang=pt</identifier>
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    <url>https://www.scielo.br/j/rbpm/a/hyBMLMXfCknGbPQjpkmxZrg/?format=pdf&amp;lang=pt</url>
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    <recordCreationDate encoding="marc">240628</recordCreationDate>
    <recordChangeDate encoding="iso8601">20240628093959.0</recordChangeDate>
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      <languageTerm authority="iso639-2b" type="code">por</languageTerm>
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