| 000 | 02643nab a2200301 i 4500 | ||
|---|---|---|---|
| 003 | BR-BrBNA | ||
| 005 | 20241004173913.0 | ||
| 008 | 241004b2024 bl.qr|pooa||| 00| 0 eng | | ||
| 040 |
_aBR-BrBNA _beng |
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| 072 | _aF60 | ||
| 100 | _aPinheiro, Mariana Faccini | ||
| 100 | _aSiqueira, Amanda Keller | ||
| 100 | _aSeki, Meire Christina | ||
| 100 | _aCarrasco, Adriano de Oliveira Torres | ||
| 100 | _aBagatini, Margarete Dulce | ||
| 100 | _aYamazaki, Ricardo Key | ||
| 245 | _aAntimicrobial activity of Achyrocline satureioides (Lam.) DC. extract in a potentizing solution | ||
| 500 | _aPublicação on-line; 47 ref.; 3 tables; Summary (En) | ||
| 520 | _a ABSTRACT Achyrocline satureioides (Lam.) DC. is a medicinal plant traditionally used in Brazilian ethnomedicine through infusion and decoction for various therapeutic purposes. The objectives were to determine the antimicrobial activity of the A. satureioides extract against Pseudomonas aeruginosa and to describe a novel technique using iron dextran solution to enhance the activity of bioactive compounds and antimicrobial agents. The extract was characterized for phytochemical composition, antioxidant activity in vitro, and antimicrobial activity. The extract exhibited a high content of phenolic compounds and considerable antioxidant activity. Concerning the antimicrobial activity, it inhibited the development of the strain at low concentrations, with a minimum inhibitory concentration (MIC) of 0.0390 mg/ml for the pure extract and 0.0195 mg/ml for the extract diluted in iron dextran, thus presenting bacteriostatic activity at these concentrations. It showed a bactericidal activity from 10 mg/ml, with inhibition halo of 2.11±0.19 and 2.22±0.50 mm for the pure extract and 2.55±0.19 and 2.66±0.33 mm for the extract diluted in iron dextran in the disk diffusion and punch hole methods, respectively. A. satureioides has an important antimicrobial activity, and the iron dextran solution enhanced the effect of bioactive compounds and antimicrobial agents. Keywords: Iron dextran, Macela infusion, Traditional medicine, Medicinal plant, Pseudomonas aeruginosa. | ||
| 650 | _aPLANTA MEDICINAL | ||
| 650 | _aMACELA | ||
| 650 | _aMEDICINA | ||
| 650 | _aPSEUDOMONAS AERUGINOSA | ||
| 773 | 0 |
_03543 _9345108 _dBotucatu-SP Instituto de Biociências - Departamento de Química e Bioquímica 1998 _o2024-5539 _tRevista Brasileira de Plantas Medicinais (Brazil) _x1516-0572 _gv. 26(1) p. 20-26; (2024) _wBR2024002650 |
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| 856 | _uhttps://www.sbpmed.org.br/admin/files/papers/file_E9twV2JfSOjX.pdf | ||
| 942 | _cANA | ||
| 999 |
_c327946 _d327946 |
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